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See all ads on AdLibrary →Pendulum (formerly Whole Biome) is a San Francisco-based precision probiotic company founded in 2012 by Colleen Cutcliffe (CEO, PhD Biochemistry from Johns Hopkins), John Eid, and Orville Chichester. The company spent nearly a decade developing proprietary probiotic strains with published peer-reviewed clinical evidence before launching its flagship Pendulum Glucose Control product in 2020 — the first probiotic classified as a medical food for the dietary management of type 2 diabetes. The probiotic strains are designed to restore gut microbiome functions that produce butyrate and stimulate natural GLP-1 release, positioning Pendulum directly in the metabolic health category at the exact moment GLP-1 drugs like Ozempic dominated cultural conversation. A subsequent GLP-1 Probiotic product extended this positioning. Pendulum scaled DTC through performance marketing and physician recommendation channels, building a subscription business around premium-priced clinical-grade formulations.
